The National Park is close to the northeast of South Africa, in the eastern part of the province of Limpopo and Mpumalanga. Phalaborwa, Limpopo is the only province in South Africa that borders the Park. The park is known to be one of the biggest parks in the world. The area covers 19,485 km2 (7,523 sq mi). On the north and south of the National Park, these two rivers are in the province of Limpopo. Boundaries are placed around the area the highest point in the park are hills called Khandzalive. Several rivers run through the park from west to east, including the Sabie, Olifants, Crocodile, Letaba, Luvuvhu, and Limpopo Rivers.
The Park climate and Lowveld is tropical, especially a hot semi-arid climate from September until May is known to be a rainy season. The climax changes begin in the rainy season in October. the park spans 360 kilometers or 220 miles from north to south, climate does change. Skukuza in the southern part of the park is about 2 to 3 °C (3.6 to 5.4 °F) cooler the whole year than Pafuri in the north, with significantly more rainfall.